The Prevail Global Study is a research project to check if a new heart treatment is safe and works well. This study focuses on people with heart problems needing a procedure called percutaneous coronary intervention (PCI). PCI is used to open up blood vessels in the heart that are blocked or narrowed. The study has two parts: one for people with in-stent restenosis (ISR), where a previously placed stent has narrowed again, and another for those with new small vessel disease (DNSV). Participants will be in the study for up to 5 years, attending regular check-ups.
- Study involves about 65 sites and lasts 12 months for enrolling participants.
- Participants will have follow-up visits for up to 5 years.
- Must be 18 or older and able to follow study rules; some health conditions may disqualify participation.