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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Researching treatment options for children with specific Wilms tumors.

Recruiting
30 years and younger
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT) This study is examining how using risk factors like tumor biology and response to therapy can improve treatment for children with FHWT, a common kidney cancer in kids. The study is looking into different treatment plans based on the stage of cancer and the child's age to see if they can lower the chance of the cancer coming back. The study will involve different chemotherapy drugs or just observation, depending on the risk factors. It aims to find the best treatment strategies while ensuring children receive the least intense treatment needed to cure them.
  • The study lasts up to 10 years, with patients being followed up after treatment.
  • Participants may receive different treatments or observation based on cancer stage and risk factors.
  • Children under 30 years with newly diagnosed FHWT are eligible.
Children participating in this study need to be under 30 years old and have a confirmed diagnosis of FHWT. Participation involves different medical tests and procedures like nephrectomy (kidney removal) and chemotherapy, with follow-up visits to monitor progress.
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Study details
    Stage I Mixed Cell Type Kidney Wilms Tumor
    Stage II Mixed Cell Type Kidney Wilms Tumor
    Stage III Mixed Cell Type Kidney Wilms Tumor
    Stage IV Mixed Cell Type Kidney Wilms Tumor

NCT06401330

Children's Oncology Group

23 August 2025

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