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SynKIR-310 for Relapsed/Refractory B-NHL

Join a trial for SynKIR-310 for tough B-NHL cases.

Recruiting
18 years and older
All
Phase 1

This study is testing a new treatment called SynKIR-310 for people with a type of cancer called B-NHL (B-cell Non-Hodgkin Lymphoma). It is for those whose cancer has come back or didn't respond after trying other treatments. Participants will receive one IV dose (medicine given through a vein) to see if it is safe and works well. The study will include up to 18 people and will take place in different centers. Two groups will first try different doses to find the best one for future studies. Once the best dose is found, more people will join to help learn more about how the treatment works.

  • The study involves a single infusion of SynKIR-310.
  • Participants must be 18 or older and have tried at least two other treatments.
  • Cannot have certain health issues like uncontrolled infections or heart problems.
Study details
    B Cell Lymphoma
    NHL
    Adult
    Mantle Cell Lymphoma
    Relapsed Non-Hodgkin Lymphoma
    Refractory Non-Hodgkin Lymphoma
    Aggressive B-Cell Non-Hodgkin Lymphoma
    Indolent B-Cell Non-Hodgkin Lymphoma
    Follicular Lymphoma
    Marginal Zone Lymphoma
    DLBCL - Diffuse Large B Cell Lymphoma
    HGBL With MYC and BCL2 and/or BCL6 Rearrangements
    High-grade B-cell Lymphoma
    Diffuse Large B Cell Lymphoma
    Large B-cell Lymphoma
    T-Cell/Histiocyte Rich Lymphoma
    Non-hodgkin Lymphoma
    B Cell
    Primary Mediastinal Large B-cell Lymphoma (PMBCL)
    Epstein-Barr Virus Positive DLBCL
    Nos
    Follicular Lymphoma Grade 3B
    DLBCL (Diffuse Large B-Cell Lymphoma) Associated With Chronic Inflammation
    High Grade B-Cell Lymphoma
    Not Otherwise Specified
    Follicular Lymphoma Grade 3
    Marginal Zone Splenic Lymphoma
    DLBCL

NCT06544265

Verismo Therapeutics

7 March 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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