This study wants to see how well a blood test can help find cancer in people who might have it. People aged 45 and older who show signs that could mean cancer will be enrolled. If you haven't been treated for cancer yet but have symptoms, you'll get a blood test. However, you won’t know the results of this test. Doctors will find out if you have cancer through their usual methods, like tests and scans. They won't see the results of the blood test, and the test won't affect their decisions.

• **Time**: You need to give a blood sample and go through standard cancer check-ups.
• **Eligibility**: You should be 45 or older with symptoms that might suggest cancer. You can't join if you had certain cancers before or are pregnant.
• **Confidentiality**: Neither you nor your doctor will see the blood test results; it's for research only.