This study is testing a new medicine called **K-645** to help with **migraine** attacks. A migraine is a type of headache that can last for hours or even days, causing severe pain. In this study, some patients will get K-645, and some will get a placebo (a pill that doesn't have medicine) to see which works better. The study is **double-blind**, meaning neither the doctors nor the patients know who gets which treatment. This helps make the results more reliable.

• The study is for adults aged 18-65 who have frequent migraines.
• Participants must visit the study center multiple times and keep a diary about their migraines.
• Pregnant women or those planning to become pregnant cannot join.

Participants should have a smartphone to use a special app for the study. It's important to read and sign a consent form before joining. This study is carefully controlled, and participants must agree to use birth control if they are of childbearing age.