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Kidney Transplant Preemptive Therapy or Prophylaxis for CMV Prevention in D+R Recipients

Studying CMV prevention in kidney transplant recipients.

Recruiting
18 years and older
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study looks at preventing cytomegalovirus (CMV), a virus that can make you sick after a kidney transplant. This is important for people getting a kidney from a donor who had CMV before. There are two ways to prevent CMV after a transplant: preemptive therapy (PET) or antiviral prophylaxis (AP). In this study, one group will get daily medicine (AP) for 200 days, and the other group will have their blood checked weekly for 100 days to see if they need medicine (PET). The study will last up to 5.5 years, with about 360 people participating.

  • Study lasts up to 5.5 years with check-ups and follow-ups.
  • Participants must be 18 or older and have a kidney transplant from a CMV-positive donor.
  • Participants must not be allergic to the medications used in the study.
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Study details
    Cytomegalovirus (CMV)
    Kidney Transplant; Complications
    Kidney Diseases

NCT06798909

University of California, San Francisco

7 March 2026

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