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ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

Comparing surgery and Trilogy™ for aortic regurgitation treatment.

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Phase N/A
**Study Brief:** This study compares two ways to treat a heart problem called **aortic regurgitation (AR)**, where the heart valve doesn't close properly, causing blood to flow backward. The study looks at the *Trilogy Transcatheter Heart Valve (THV) System* and traditional **Surgical Aortic Valve Replacement (SAVR)**. Researchers aim to show that the Trilogy THV is not worse than SAVR for treating AR. **Eligibility:** To join the study, you need to have a certain level of AR and be able to have either Trilogy THV or SAVR. You must be old enough to agree to the study and willing to attend follow-up visits. You cannot join if your AR is not severe enough, if you have other serious health problems, or if you’re not a candidate for the procedures. **Key Points:** - **Duration:** The study requires follow-up visits after the procedure. - **Eligibility:** You must meet specific health criteria to participate. - **Risks and Benefits:** Consider potential risks and benefits of each treatment option. Please discuss with your doctor to see if this study is right for you.
Study details
    Aortic Regurgitation
    Aortic Valve Insufficiency
    Aortic Insufficiency

NCT06608823

JenaValve Technology, Inc.

23 August 2025

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