HPV Vaccine Reduced Dose Study is looking to see if getting one shot of the HPV vaccine works just as well as getting two or three shots. HPV, or Human Papillomaviruses, can cause cancers in different parts of the body, and the vaccine helps prevent this. The study involves checking the body's defense system, called the immune response, in the blood, lymph nodes (which are parts of the body that help fight infections), and bone marrow (where blood cells are made).

Participants must be healthy adults aged 18-45 who have never had the HPV vaccine or any HPV-related diseases. They will get one or two doses of the vaccine and can complete the series later. During the study, participants will have blood tests and small samples taken from the lymph nodes and bone marrow. This research could help create better vaccines in the future.

• Study lasts for a specific period, with multiple visits required.
• Participants must be comfortable with blood draws and needle procedures.
• No participation if there are allergies to vaccines or certain medical conditions.