Image

A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

Testing Teplizumab's effects on Type 1 Diabetes in young participants.

Recruiting
1-25 years
All
Phase 3

Study Overview: This study aims to check how well a medicine called teplizumab works compared to a placebo (a fake treatment) in kids and young adults aged 1 to 25 who have recently been diagnosed with Stage 3 Type 1 Diabetes (T1D). This study will take about 18 months for each participant. Teplizumab and placebo are given through an IV, which means it's put directly into a vein.

Type 1 Diabetes (T1D) is a condition where the body can't produce insulin, a hormone that helps control blood sugar. Stage 3 means the disease is more advanced.

  • The study will last 18 months for each person.
  • Participants must be between ages 1 and 25.
  • Involves regular IV infusions and check-ups.

Eligibility: Participants must have a recent Stage 3 T1D diagnosis and test positive for T1D-related antibodies. Women must use effective birth control if they can have children. People with other types of diabetes, certain infections, or recent vaccinations can't join.

Before joining, it's important to understand the study's requirements and risks. Always talk to a doctor for more details.

Study details
    Type 1 Diabetes Mellitus

NCT07088068

Sanofi

16 August 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.