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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Researching KarXT + KarX-EC for memory issues in Alzheimer's patients.

Recruiting
60-85 years
All
Phase 3

This study is testing a new treatment, KarXT + KarX-EC, for people with memory and thinking problems caused by Alzheimer's disease. Alzheimer's is a brain disease that makes it hard to remember things and think clearly. This study is for people in the mild to moderate stages of the disease. Participants need a caregiver who can help them during the study and attend visits with them. They also need to have been taking certain Alzheimer's medicines steadily for at least 12 weeks.

Some people cannot join the study, like those with other serious mental health issues or liver problems. If you've been treated with certain Alzheimer's drugs recently or have specific brain scan findings, you might not be eligible either.

  • The study requires several visits and ongoing participation.
  • Participants must have a caregiver to assist during the study.
  • Stable medication use is necessary for those already on Alzheimer's drugs.
Study details
    Alzheimer's Disease

NCT06976216

Bristol-Myers Squibb

23 August 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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