Study Overview: This study is testing a new drug called VK2735 to help with weight loss. It's a "Phase 3" study, which means it's a late stage of research where the medicine is given to more people to see if it's safe and works well. **Double-blind** means neither the doctors nor the patients know if they're getting the real medicine or a fake one (placebo). The study lasts for 78 weeks, which is almost 1.5 years.

Eligibility: Adults 18 or older with a body mass index (BMI) of 30 or more, or 27 or more if they have other health issues like high blood pressure or heart problems, can join. **BMI** is a number calculated from your height and weight to check if you're overweight or obese. People who recently lost or gained a lot of weight or have diabetes cannot participate.

• The study will take about 78 weeks, which is a long time commitment.
• Participants will be checked for safety and any side effects during the study.
• Eligibility includes specific health conditions and age requirements.