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A Study Evaluating the Effect of Daily Oral RO7795081 in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity

Join a study testing a new pill for weight-related health issues.

Recruiting
18 years and older
All
Phase 2
**Study Overview:** This study looks at how a medicine called RO7795081 taken by mouth every day affects adults who are overweight or obese. These adults must have at least one health problem related to their weight, like high blood pressure, but cannot have diabetes. The study is double-blind, which means neither the participants nor the researchers know who is receiving the actual medicine or a placebo (a harmless pill with no effect). This helps make the results fair. **Who Can Join:** Adults with a BMI of 30 or more, or those with a BMI between 27 and 30 who have a weight-related health problem can join. Participants should have tried losing weight before and have had a stable weight for the past 3 months. **Who Cannot Join:** People with diabetes, certain genetic conditions, recent heart issues, or those on extreme diets cannot participate. **Key Points:** - **Study Length:** Involves multiple visits over time. - **Compensation:** Participants may receive payment. - **Risks:** Potential side effects as with any medication. *Joining this study helps researchers understand how well RO7795081 works and how safe it is for those with weight issues.*
Study details
    Obesity or Overweight

NCT07081958

Hoffmann-La Roche

23 August 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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