Image

A Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Variant-containing Formulations

Testing new COVID-19 vaccines for safety and immune response.

Recruiting
12 years and older
All
Phase 4
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing a new type of COVID-19 vaccine called mRNA-1283, also known as mNEXSPIKE®. The goal is to see if this vaccine is safe and helps the body fight off new versions of the virus. People who can join the study are either 65 years or older, or between 12 to 64 years with certain health risks that make COVID-19 more dangerous for them. If you're interested, you should not have had COVID-19 recently and should not have recently been vaccinated against COVID-19.

  • The study involves receiving a new COVID-19 vaccine and follow-up visits.
  • Participants must use birth control if they can become pregnant.
  • Participants should not have had other vaccines recently, except the flu shot.

Before joining, participants will have a health check to ensure they meet all the study rules. This study helps us learn more about how vaccines can protect us from different COVID-19 variants.

Print
Study details
    COVID-19

NCT07089706

ModernaTX, Inc.

2 August 2025

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.