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Trans-auricular Vagal Nerve Stimulation as an Innovative Approach to the Treatment of Pain in Pediatric Patients Suffering From Sickle Cell Disease

Trying new ear nerve stimulation for pain relief in kids with Sickle Cell.

Recruiting
7-18 years
All
Phase N/A
**Study Summary** This study aims to test a new way to help children with Sickle Cell Disease (SCD) manage their pain. Sickle Cell Disease is a condition where red blood cells are shaped like sickles, causing pain and other health problems. Currently, many SCD patients use strong pain medication like opioids, which can have bad side effects. The study will use a device called *transcutaneous auricular vagal nerve stimulation* (taVNS). This device uses tiny electrical signals on the ear to help reduce pain by calming the body's response to pain and lowering inflammation. **Key Points:** - The study will examine how well kids tolerate and accept using the taVNS device. - Researchers will check if the device helps reduce pain by looking at different health signs and pain levels. - The study is open to kids with normal ear anatomy who have been in the hospital for SCD pain at least once before. This research could lead to a safer, non-drug way to manage pain in kids with SCD, reducing their need for opioids.
Study details
    Sickle Cell Disease

NCT07090668

Emory University

2 August 2025

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