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A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

Study testing JNJ-90301900 with treatments for lung cancer.

Recruiting
18 years and older
All
Phase 2

This study is looking at how well a new medicine called JNJ-90301900 works when added to existing treatments for a type of lung cancer called Non-Small Cell Lung Cancer (NSCLC). Patients with locally advanced, non-removable stage III NSCLC will first receive a combination of chemotherapy (a treatment using special drugs) and radiation therapy (using high-energy rays to kill cancer cells), known as cCRT. After that, they will receive consolidation immunotherapy (cIT), which helps the immune system fight cancer. The study will see if this combination improves the objective response rate (ORR), meaning how well the cancer responds to treatment.

  • Study participation requires multiple visits for treatments and check-ups.
  • There may be risks, including allergic reactions to the treatment.
  • Compensation for participation is not mentioned.

To join, you must be diagnosed with NSCLC within the last 3 months and be able to get the standard treatment. Some health conditions, like heart problems or other cancers, may prevent you from joining. Always talk to your doctor about whether this study is right for you.

Study details
    Carcinoma
    Non-Small-Cell Lung

NCT06667908

Johnson & Johnson Enterprise Innovation Inc.

7 March 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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