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A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

Exploring a new treatment for advanced breast cancer.

Recruiting
18 years and older
All
Phase 1

This study is about testing a new drug called MEN2312 for people with advanced breast cancer. Advanced breast cancer means the disease has spread and cannot be fully cured. MEN2312 is being tested because it might help stop the cancer from growing. MEN2312 works by blocking a part of the cell called lysine acetyltransferase 6 (KAT6), which can be involved in cancer growth.

Key Points:

  • The study is only for adults who have tried other treatments without success.
  • Participants must have certain genetic changes in their tumor tissue.
  • People with severe brain involvement or major organ issues cannot join.

Participants can have had up to 6 prior treatments, including certain chemotherapies. Before joining, doctors will check if this is a good fit. If you have breast cancer that has not responded to other treatments and meets the study's criteria, you might consider participating. Always discuss with your doctor before joining any study to understand the benefits and risks involved. This study offers a chance to try a new treatment option.

Study details
    Advanced Breast Cancer

NCT06638307

Stemline Therapeutics, Inc.

21 March 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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