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A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

Study on SAR442970's effects and safety for adults with ulcerative colitis.

Recruiting
18-75 years
All
Phase 2
This study is testing a new medicine, SAR442970, for adults with **Ulcerative Colitis** (UC), a disease that causes inflammation in the colon. This is a *phase 2b study*, which means it's looking at how well the medicine works and if it's safe. It's a *randomized* and *double-blind* study, so neither the participants nor the researchers know who is getting the medicine or a placebo. The study lasts up to 168 weeks, with 158 weeks of treatment. Some people may take part in an *open-label* period where they know they are getting the medicine for up to 104 weeks. Key Points: - Participants spend up to 168 weeks in the study, including potential long-term treatment. - **Eligibility**: Ages 18-75 with moderate to severe UC and prior treatment history. - Some exclusions: other bowel diseases, recent infections, or certain health conditions. This is not all the information about the study. If you're interested, you should contact the study team for more details.
Study details
    Ulcerative Colitis

NCT06975722

Sanofi

16 August 2025

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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