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A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)

We're studying cell safety for young and pediatric heart patients.

Recruiting
4-30 years
All
Phase 1
This study is to see if a new treatment using cells called *allogeneic neonatal mesenchymal stromal cells* (nMSCs) can help people with *Dilated Cardiomyopathy* (DCM). DCM is a heart problem where the heart gets bigger and weaker. This study checks if nMSCs can make the heart work better. The study is for young adults (18-30 years old) and kids (4-18 years old). Participants will get three infusions of nMSCs through a needle in their vein every 30 days. Doctors will check the heart’s health before and after treatment using tests like echocardiograms and MRIs. Participants will have checkups for 14 months, including phone calls and visits. There will be some payments for joining, and kids can stay overnight near the hospital after getting the treatment. **Key Points:** - The study will last for 14 months with several checkups. - Participants will receive three treatments, one every month. - There is financial compensation for attending visits. Remember, if you're interested, your heart doctor needs to approve your participation and you'll need to sign a consent form.
Study details
    Dilated Cardiomyopathy

NCT06464588

Emory University

13 September 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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