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A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment

Researching Codrituzumab for kids/teens with hard-to-treat solid tumors.

Recruiting
1-21 years
All
Phase 1

This study is looking at a treatment called *codrituzumab* for kids and young adults who have solid tumors. *Solid tumors* are lumps of cancer cells, and *codrituzumab* is a medicine researchers want to test for safety and side effects. The study will also explore how the body handles this medicine. Participants need to be between 1 and 21 years old and have a tumor that didn’t respond to regular treatments or came back after treatment. It's important that their tumor makes a protein called *GPC3*. This protein will be checked before joining the full study.

  • *Study Length*: You might be in this study for a while, including visits to the hospital or clinic.
  • *Risks*: There could be side effects from the treatment, which the doctors will monitor closely.
  • *Eligibility*: Participants must not be on other cancer treatments or have certain health issues.
Study details
    Primary Extra-cranial Solid Tumor
    Recurrent or Refractory Glypican 3 (GPC3)

NCT04928677

Memorial Sloan Kettering Cancer Center

5 July 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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