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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

Participate in a study for heart failure treatment with Omecamtiv Mecarbil.

Recruiting
18-85 years
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

Omecamtiv Mecarbil Study for Heart Failure: This study looks at whether a new drug, *omecamtiv mecarbil*, can help people with serious heart problems. Heart failure is when the heart doesn’t pump well. *Ejection fraction* is a measure of how well the heart pumps. A *reduced ejection fraction* means the heart is very weak. The study compares the drug to a placebo (a pill with no medicine) to see if it prevents hospital stays, heart surgeries, or death. The study lasts up to 3 years and ends when 850 participants have a heart event or heart-related death. People aged 18-85 with certain heart conditions can join. Some people cannot join, including those recently having heart surgeries or taking certain medications.

  • Study lasts up to 3 years.
  • Participants receive either the study drug or a placebo.
  • At least 850 participants will be involved.
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Study details
    Heart Failure
    Heart Failure With Reduced Ejection Fraction

NCT06736574

Cytokinetics

5 July 2025

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