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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

Join a study for heart failure treatment with Omecamtiv Mecarbil.

Recruiting
18-85 years
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing a drug called *omecamtiv mecarbil* to see if it helps people with serious *heart failure*. Heart failure is when the heart doesn't pump blood as well as it should. The study focuses on people with a severely reduced *ejection fraction*, which is a measure of how much blood the heart pumps out with each beat. Participants will be split into two groups: one group will get the drug, and the other will get a placebo (a pill that does nothing). The study lasts up to 3 years and aims to find out if the drug can reduce the risk of events like heart failure hospitalizations or heart-related deaths.

  • Participation may last up to 3 years.
  • Participants need to be between 18 and 85 years old.
  • Must have a history of chronic heart failure and be on certain medications.

If you have severe heart failure and meet the study's criteria, this study could offer a chance to try a new treatment. However, always consider potential risks and discuss participation with your doctor.

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Study details
    Heart Failure
    Heart Failure With Reduced Ejection Fraction

NCT06736574

Cytokinetics

7 March 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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