This study looks at how a new medicine called orforglipron helps people with obesity (very overweight) or those who are overweight and have Type 2 Diabetes (a condition where the body doesn't use insulin properly). A placebo (a harmless pill with no medicine) will also be used to compare results. The study lasts about 18 months.

Eligibility: Participants need a Body Mass Index (BMI) of 25 or higher. BMI measures if you're at a healthy weight. You must have Type 2 Diabetes with a hemoglobin A1c (HbA1c) level between 7% and 10%. HbA1c shows how well your blood sugar is controlled. You should have tried at least once to lose weight through dieting.

Key Points:

• The study lasts for about 18 months.
• Certain health conditions, like Type 1 Diabetes or heart issues, mean you can't join.
• Participants can't take other weight-loss medicines during the study.