This study is for people with HIV (a virus that affects the immune system) who also have Alcohol Use Disorder (AUD), which means having problems controlling alcohol drinking. The study will test if using a medicine in a new way (called off-label) can help people drink less. Participants will attend a 12-week program where they will get counseling from a clinical pharmacist to help change their drinking habits. They will also receive a medicine called varenicline to see if it helps them reduce alcohol use.

• The study lasts for 12 weeks and includes various assessments such as interviews and lab tests.
• Participants must have HIV, be 18 or older, and meet criteria for alcohol use disorder, among other conditions.
• People already receiving treatments for alcohol use, pregnant, or with certain health issues cannot join.

Participants need to be able to attend study visits, have a cell phone for contact, and can give written consent to join. They will be asked to bring medication bottles to visits to check how well they are following the treatment.