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Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)

Exploring laser treatment for heart artery calcium buildup.

Recruiting
18 years and older
All
Phase N/A

The FRACTURE Trial is a study where doctors use a special tool called the Bolt Intravascular Lithotripsy System to help treat people with coronary artery disease. This system uses sound waves to break up hard calcium deposits in the arteries, making it easier for a balloon to open them up. This is for people who have stable or unstable angina, silent ischemia, and need a procedure called Percutaneous Coronary Intervention (PCI). Participants must be 18 years or older and cannot have had a heart attack within the last 30 days.

  • The study involves using a new treatment method that is not yet approved for regular use.
  • Participants will not be randomly selected; everyone in the study will receive the same treatment.
  • Some people may not qualify due to recent heart attacks, advanced heart failure, or severe kidney disease.

Consider if you meet the criteria and are comfortable with the study requirements before participating.

Study details
    Coronary Artery Disease
    Coronary Artery Calcification

NCT06181240

Bolt Medical

14 June 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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