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A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Study on side effects and movement of IV drug for lung cancer.

Recruiting
18 years and older
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

In this study, researchers are looking at how safe a new drug called telisotuzumab vedotin is for adults with a type of lung cancer called non-small cell lung cancer (NSCLC). NSCLC is a disease where cancer cells grow in the lungs. The drug is given through a needle into a vein, known as an intravenous (IV) infusion. About 150 adults will get different doses of the drug over three years. The study will take place in 70 to 80 places around the world.

  • Time Commitment: The study lasts for three years, with regular visits to a hospital or clinic.
  • Potential Risks: Some side effects may occur, and the treatment might be more demanding than usual care.
  • Eligibility: Participants need specific types of lung cancer and must have tried at least one other treatment.

Doctors will check how the drug affects the cancer and watch for side effects. They will also do blood tests and ask questions to see how participants are feeling. This study is for people who have already tried other treatments for their lung cancer. Participants should be ready for regular hospital visits and tests.

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Study details
    Non-Small Cell Lung Cancer

NCT06568939

AbbVie

7 March 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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