Study Overview: This study is testing if a lower dose of radiation therapy (RT) after chemotherapy helps treat children with a type of brain tumor called CNS germinoma. Chemotherapy involves drugs like Carboplatin and Etoposide, which help stop cancer cells from growing. Radiation therapy uses high-energy waves to kill cancer cells.
Key Points:
- This study lasts up to 120 months with follow-up visits after treatment.
- Patients will receive chemotherapy and then radiation therapy, with the number of sessions depending on their response to treatment.
- Participants will have regular health checks, including MRI scans and optional blood tests.
Eligibility: Children aged 3 to under 30 with newly diagnosed CNS germinoma can participate. They must have certain medical tests done before joining. Pregnant girls or those who have had other cancer treatments (besides surgery and certain medicines) cannot join. All participants and their guardians must agree to the study rules.