This study is for people with a serious yeast infection called **invasive candidiasis**. The infection is usually caused by a fungus called **Candida**. Participants in the study will first receive medicine through a needle in their vein (this is called an **intravenous or IV** treatment) with a drug called **echinocandin**. After that, they will take one of two oral medicines (pills): **ibrexafungerp** (also known as SCY-078) or **fluconazole**. The study involves people who are 18 years or older and have proof of a Candida infection in their blood or tissue. However, certain infections like those in the brain, heart, or bones, or if they have other serious fungal infections, will not qualify for the study. **Key Points:** - The study involves taking IV echinocandin followed by oral medication. - Participants should not have had more than 48 hours of non-echinocandin antifungal treatment recently. - People with certain severe liver issues or other fungal infections cannot join. This research will help find the best treatment regimen for patients with invasive candidiasis. If you qualify, it could be a good opportunity to receive treatment and contribute to important medical research.