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A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Testing Glofitamab with chemotherapy for relapsed lymphoma safety and effectiveness.

Recruiting
18 years and older
All
Phase 1
This study tests a treatment for a type of blood cancer called **diffuse large B-cell lymphoma (DLBCL)**. The treatment combines three drugs: *glofitamab*, *gemcitabine*, and *oxaliplatin*. Researchers want to see if this treatment is safe and works well for people whose cancer has come back or didn't respond to treatment. To join the study, patients must have a certain type of DLBCL and have tried at least one other treatment before. They cannot join if they have certain other health problems or if they've had some specific treatments in the past. **Key Points:** - The study involves taking medications and regular check-ups. - Participants cannot have recent major infections or certain health issues. - The study aims to include people from different racial and ethnic backgrounds in the U.S. It's important for patients to consider their health conditions and past treatments to see if this study is suitable for them.
Study details
    Lymphoma

NCT06624085

Hoffmann-La Roche

7 June 2025

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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