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Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)

Testing ruxolitinib cream for hidradenitis suppurativa safety and effectiveness.

Recruiting
12 years and older
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)
Study Overview: This study is testing a cream called ruxolitinib to see if it works and is safe for people with a skin condition called hidradenitis suppurativa (HS). This condition causes painful lumps under the skin, often in areas where skin rubs together. Key Points:
  • Participation Duration: The study includes a controlled period followed by an extension, lasting several weeks.
  • Visits and Treatments: Participants cannot use certain antibiotics or skin products during specific periods of the study.
  • Risks and Exclusions: People with certain medical conditions, pregnant women, or those with large affected skin areas may not join.
Eligibility: To join, you must have had HS for at least 6 months and show mild to moderate symptoms without severe skin issues like large draining tunnels. You also need to avoid using certain skin treatments during the study. However, if your skin issues cover too much of your body, or if you have certain health problems, this study might not be for you. It's important not to be pregnant or planning a pregnancy during the study.
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Study details
    Hidradenitis Suppurativa

NCT06958211

Incyte Corporation

6 June 2026

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