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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

Join a study on LY3457263 for Type 2 Diabetes management.

Recruiting
18-75 years
All
Phase 2

This study tests a new drug, LY3457263, for people with Type 2 Diabetes who aren't reaching their blood sugar goals with semaglutide or tirzepatide. The key measure is the change in hemoglobin A1c (HbA1c), which shows average blood sugar over a few months.

Eligibility: To join, you need Type 2 Diabetes, a body mass index (BMI) over 27, and stable weight and medication for the past three months. You cannot participate if you have Type 1 Diabetes, recent heart problems, or have used insulin in the past year.

Key Points:

  • **Duration**: The study lasts about 9 months.
  • **Treatment**: You must be on stable doses of semaglutide or tirzepatide.
  • **Exclusions**: Recent heart issues or weight loss medications disqualify participation.
Study details
    Type 2 Diabetes

NCT06897475

Eli Lilly and Company

7 March 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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