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Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

Studying leg issues after lymph node mapping in early-stage endometrial cancer.

Recruiting
18 years and older
Female
Phase 3

This study looks at two different ways to help prevent leg swelling, called lymphedema, in women with stage I endometrial cancer. The study will compare standard lymph node dissection, which removes lymph nodes around the uterus, with sentinel lymph node mapping, which uses a special dye and camera to find cancer in nearby lymph nodes. The goal is to see which method causes less swelling in the legs after surgery.

  • Duration: You will be followed every 3 months for one year, then at 18 and 24 months.
  • Procedures: Involves minimally invasive surgery and possible lymph node removal.
  • Eligibility: Must be at least 18 years old, diagnosed with stage I endometrial cancer, and speak English, Spanish, or Korean.

If you're considering participating, ensure you understand the procedures involved, the follow-up schedule, and any potential risks related to the surgery. Discuss with your doctor whether this study is a suitable option for you. You will be required to provide informed consent to join the trial.

Study details
    Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

NCT05646316

NRG Oncology

19 September 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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