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Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer

Personalized treatment for low-risk endometrial cancer after surgery.

Recruiting
18 years and older
Female
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

Tailoring Therapy for Endometrial Cancer

This study is for patients with low-risk endometrial cancer who have had surgery. Endometrial cancer is a type of cancer that starts in the lining of the uterus. The study looks at the cancer tissue removed during surgery to help doctors decide if more treatment, like radiation or chemotherapy, is needed. The goal is to see if this approach helps prevent the cancer from coming back.

Key Points:

  • Participants will have check-ups after treatment at 3 and 6 months, then every 6 months for 3 years, and then yearly.
  • Participants may need additional treatments like radiation, depending on the cancer's characteristics.
  • Participants will undergo imaging tests such as chest x-rays and CT scans to monitor the cancer.

Participants must have had a hysterectomy, which is surgery to remove the uterus, and be at least 18 years old. They must also be able to communicate in English or French to complete questionnaires. Joining the study means regular visits to the doctor and possibly more treatment to prevent the cancer from coming back.

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Study details
    Stage I Uterine Corpus Endometrial Stromal Sarcoma AJCC v8
    Stage II Uterine Corpus Endometrial Stromal Sarcoma AJCC v8
    Stage III Uterine Corpus Endometrial Stromal Sarcoma AJCC v8

NCT06388018

NRG Oncology

25 May 2025

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