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Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer

Customizing care for patients with low-risk endometrial cancer post-surgery.

Recruiting
18 years and older
Female
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is for patients who had surgery for low-risk endometrial cancer, a type of cancer that affects the lining of the uterus. After surgery, the removed tissue is checked in a lab to see if more treatment is needed. This may include radiation or chemotherapy.

  • This study lasts for 3 years, with follow-up visits every 6 months for the first 3 years, and annually afterward.
  • Patients may need imaging tests like chest X-rays, CT scans, or MRIs during the study.
  • No previous chemotherapy or radiation for the current cancer diagnosis is allowed for this study.
The study looks at how well personalized treatment works and checks if more tests can help predict the cancer's behavior. Patients may be monitored or given specific radiation treatments based on their cancer type.

To be eligible, patients must have had surgery, be at least 18 years old, and able to complete study questionnaires. The study also requires that patients are available for treatment and follow-up visits. Participants must agree to return to their care facility for any side effects during the study.

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Study details
    Stage I Uterine Corpus Endometrial Stromal Sarcoma AJCC v8
    Stage II Uterine Corpus Endometrial Stromal Sarcoma AJCC v8
    Stage III Uterine Corpus Endometrial Stromal Sarcoma AJCC v8

NCT06388018

NRG Oncology

25 May 2025

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