The study tests the **SpaceIT Hydrogel System** to see if it's safe and works well for men with prostate cancer getting **External Beam Radiotherapy (EBRT)**. EBRT is a type of radiation treatment that targets cancer cells from outside the body. The study has two groups: one group will receive the new SpaceIT Hydrogel while the other will get a different type of hydrogel spacer already on the market. The hydrogel creates a space between the prostate and the rectum to help protect healthy tissue from radiation.

• **Time Commitment**: Participation may require multiple visits to the clinic.
• **Compensation**: There may be compensation for time and travel.
• **Risks**: As with any study, there are risks which will be explained before you join.

To join, you must be 18 or older, have prostate cancer confirmed by tests, and meet other specific health criteria. You cannot join if you've had certain prostate surgeries or other medical conditions that might interfere with the study. The study aims to ensure safety and find the best treatment options for prostate cancer patients.