Image

A Study to Investigate Efficacy, Safety, Tolerability, and Pharmacokinetics of JZP441 Compared With Placebo in Participants With Narcolepsy Type 1

Exploring new narcolepsy treatment and safety with JZP441.

Recruiting
18-64 years
All
Phase 1

Narcolepsy is a condition that makes people very sleepy during the day. This study looks at a new treatment called JZP441 for narcolepsy type 1 (NT1). The study checks how safe and effective JZP441 is for adults with NT1. It is a Phase 1b study, meaning it's an early stage of testing. The study uses a placebo (a fake treatment) to compare with JZP441. Participants won't know if they're getting JZP441 or placebo, but the sponsor will know. The study checks how the body processes JZP441, which is called pharmacokinetics (PK).

  • The study needs multiple visits and tests over time.
  • Only adults aged 18 to 64 who meet specific health criteria can participate.
  • Participants should not have certain health problems or be on other medications that may interfere with the study.
Study details
    Narcolepsy

NCT06961266

Jazz Pharmaceuticals

21 March 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.