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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

Trying a new drug, Cemiplimab, for advanced lung cancer after chemo.

Recruiting
18 years and older
All
Phase 2/3

This study is for people with advanced lung cancer, specifically non-small cell lung cancer (NSCLC), who have already had treatments like platinum chemotherapy and immunotherapy. The study is about adding a medicine called cemiplimab to usual treatments, docetaxel and ramucirumab. Cemiplimab is a type of drug called a monoclonal antibody that helps the immune system fight cancer by blocking a pathway called PD-1. Docetaxel and ramucirumab are other drugs used to stop cancer cells from growing. The study wants to see if adding cemiplimab helps people live longer and if it works better than just using docetaxel and ramucirumab alone. Participants in the study will be randomly assigned to two different groups, with one group receiving cemiplimab in addition to the usual treatment, while the other group will receive the usual treatment alone. The study involves regular visits for treatment and tests like blood samples and scans.

  • The study lasts for several weeks, with follow-ups every 3-6 months for up to 3 years.
  • Participants may need to visit the hospital for treatments and tests every 21 days.
  • Participants will receive compensation for their involvement and contribution to the study.
Study details
    Recurrent Lung Non-Small Cell Carcinoma
    Stage IV Lung Cancer AJCC v8

NCT06616584

SWOG Cancer Research Network

17 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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