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Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

Clinical trial for CCS1477 (Inobrodib) in blood cancers.

Recruiting
18 years and older
All
Phase 1/2

Study Overview: This is a Phase 1/2a study to find out if a new drug called CCS1477 (also known as inobrodib) is safe and how well it works in patients with blood cancers. These cancers include Non-Hodgkin Lymphoma, Multiple Myeloma, Acute Myeloid Leukemia, and High-Risk Myelodysplastic Syndrome. The study is also open to patients with Peripheral T-cell lymphoma.

Eligibility: To join, patients must consent to participate, have a good physical condition (ECOG 0-2), and have already tried standard cancer treatments. Patients should have normal organ function. Patients cannot join if they have had recent surgeries or taken certain drugs within a few weeks, have severe diseases, or have heart issues.

  • Study Length: The duration of participation is not specified, but it is critical to discuss it with the study team.
  • Visits: Regular visits to the study center may be required to monitor safety and effectiveness.
  • Risks: As with any clinical trial, there may be risks and side effects. Participants should talk to their doctors about these risks.
Study details
    Haematological Malignancy
    Acute Myeloid Leukemia
    Non Hodgkin Lymphoma
    Multiple Myeloma
    Higher-risk Myelodysplastic Syndrome
    Peripheral T Cell Lymphoma

NCT04068597

CellCentric Ltd.

17 May 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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