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Neonatal Platelet Transfusion Threshold Trial

Study on when to give platelet transfusions to newborns.

Recruiting
48 years and younger
All
Phase N/A

Study Overview: This study looks at very early babies born between 23 and 26 weeks to see if a lower amount of platelets in their blood is safe and better for them. Platelets help stop bleeding. Babies this early often need platelet transfusions to prevent bleeding. This study wants to see if using fewer transfusions is safe after the first week of life.

  • Length & Monitoring: Babies are monitored up to 40 weeks' age.
  • Eligibility: Babies born between 23 and 26 weeks, less than 48 hours old are eligible.
  • Randomization: Only those with specific low platelet counts are randomly picked for transfusions.

Parents must give consent for their baby to join, and some conditions like planned comfort care or certain bleeding disorders can exclude a baby. This research could change how doctors help these tiny babies and might save resources and costs in the future.

Study details
    Thrombocytopenia
    Neonatal
    Platelet Transfusion
    Infant
    Newborn
    Diseases
    Infant
    Extremely Low Birth Weight
    Infant
    Small for Gestational Age
    Thrombosis

NCT06676904

NICHD Neonatal Research Network

7 March 2026

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