This study is testing a device called the Bionic Pancreas (BP) for people with Cystic Fibrosis-Related Diabetes (CFRD). Cystic Fibrosis is a genetic disorder affecting the lungs and other organs, and CFRD is a type of diabetes related to it. The BP helps control blood sugar using only insulin. For 13 weeks, participants will either use the BP or their usual insulin method. Then, everyone will use the BP for another 13 weeks.

• This study lasts for 26 weeks.
• Participants must be at least 14 years old.
• Participants cannot have certain medical conditions or be in another diabetes study.

Participants need to use a Continuous Glucose Monitor (CGM), which keeps track of blood sugar levels. They also need someone nearby for emergencies. Participants cannot travel outside the U.S. for more than 14 days during the study. If you want to join, you need permission from a parent or guardian if you're under 18. This study is testing a new method to help manage CFRD, but there are certain rules and checks to follow to keep everyone safe.