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Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors

"Bupropion study for reducing fatigue in cancer survivors."

Recruiting
18 years and older
All
Phase 3

Bupropion is a drug used to treat depression and help quit smoking. It belongs to a group called antidepressants and works by increasing activity in the brain. This study is testing if bupropion can help reduce tiredness (fatigue) caused by cancer and its treatment. Fatigue is feeling very tired, even if you haven't done much. In this study, some people will take bupropion, and others will take a placebo (a pill that looks like the real drug but has no effect) to see which works better. The study lasts for up to 13 weeks, and involves regular medical check-ups and blood tests. You can join if you are an adult cancer survivor who feels very tired (with a fatigue score of 4 or more on a scale of 0-10) and have finished major cancer treatments.

  • Study Length: 13 weeks
  • Eligibility: Cancer survivors aged 18+, completed major treatments
  • Compensation: Not mentioned, but regular check-ups included

Note: You can't join if you're already taking bupropion or certain other medications, or if you have specific health conditions like seizures or a severe kidney issue.

Study details
    Hematopoietic and Lymphatic System Neoplasm
    Malignant Solid Neoplasm

NCT03996265

University of Rochester NCORP Research Base

10 May 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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