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Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

Study testing Baricitinib for ongoing Long COVID symptoms.

Recruiting
18 years and older
All
Phase 3

This study will test if a medicine called baricitinib, compared to a placebo (a pill with no medicine), can help with Long COVID symptoms. Long COVID is when people have problems like memory trouble, tiredness, or trouble breathing, even after recovering from COVID-19. The study will check if baricitinib helps improve brain functions, physical activities, and overall life quality for these patients.

To join, you need to be at least 18 years old and have had COVID-19 at least 6 months ago. You must also have symptoms like fatigue or "brain fog" that started after COVID-19 and have lasted for at least 6 months. You cannot join if you have other serious health conditions, are pregnant, or taking certain medicines.

  • The study will include 550 participants divided into two groups (500 and 50).
  • Participants will receive either baricitinib or placebo.
  • Symptoms and improvements will be tracked over time.

This trial seeks to find a treatment for Long COVID, which has no current effective interventions. Participants should consider their health conditions and commitments before joining.

Study details
    Long COVID
    Sars-CoV-2 Infection
    Coronavirus Infections
    COVID-19

NCT06631287

Wes Ely

3 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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