Image

A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight

Testing Tirzepatide for adults with Type 1 Diabetes and weight issues.

Recruiting
18 years and older
All
Phase 3

We're studying tirzepatide, a new treatment for adults with type 1 diabetes and obesity or overweight. Type 1 diabetes is when the body doesn't make insulin, and obesity means having too much body fat. Tirzepatide is compared to a placebo (a "fake" treatment) to see how well it works and if it's safe. The study takes about 49 weeks.

To join, you must have had type 1 diabetes and used insulin for at least a year. Your HbA1c (a blood sugar measure) should be between 7.0% and 10.5%. You need a body mass index (BMI) of 25 or higher and a steady weight for 90 days.

However, you can't join if you've had serious blood sugar problems needing hospital visits, eye treatments for diabetes, or pancreatitis. If you've used weight loss drugs recently, you are also not eligible.

  • Study lasts about 49 weeks.
  • Need to visit clinic regularly for check-ups.
  • Risks include possible side effects of tirzepatide.
Study details
    Type 1 Diabetes
    Obesity
    Overweight

NCT06914895

Eli Lilly and Company

21 June 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.