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A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH

Join a study for cirrhosis treatment caused by MASH.

Recruiting
18-75 years
All
Phase 2

This study looks into the effects of a drug called efimosfermin on people with a liver condition called MASH, which stands for metabolic dysfunction associated steatohepatitis. MASH can lead to liver scarring, known as cirrhosis. Cirrhosis is when the liver gets damaged and scarred, making it hard for the liver to work properly. The study focuses on people with compensated cirrhosis, meaning their liver is damaged but still manages to function.

Participants need to be between 18 and 75 years old and have at least two signs of metabolic syndrome, which includes conditions like high blood pressure, high blood sugar, extra body fat, and abnormal cholesterol levels. A liver biopsy, which is a tiny piece of the liver taken for testing, must confirm MASH with stage F4 fibrosis, a type of severe scarring.

  • Study length: Specific duration not mentioned, but participation involves multiple visits.
  • Compensation: Not specified, but often studies offer some form of compensation.
  • Risks: Must not have other liver diseases or type 1 diabetes.
Study details
    Metabolic Dysfunction-Associated Steatohepatitis

NCT06920043

Boston Pharmaceuticals

7 March 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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