The study is testing a new device called the Laminar Left Atrial Appendage Closure (LAAC) to see if it is safe and works well for people with non-valvular atrial fibrillation (NVAF). NVAF is a heart condition where the heart beats irregularly, which can lead to strokes (when blood flow to the brain is blocked). The study will compare the new device to existing devices like WATCHMAN™ and Amulet™. Participants in the study must have NVAF, a specific score (CHA2DS2-VASc) that shows their stroke risk, and a reason to try something other than regular blood-thinning medicines. They also need to be able to follow the study rules and agree to join.

Key Points:

• The study is open-label and randomized, meaning participants will be randomly assigned to different groups.
• The study might require regular check-ups and following a specific post-procedure medication plan.
• Participants need to be willing to provide written consent and comply with study requirements.