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A Study to Evaluate the Efficacy and Safety of Once-Weekly MET097 in Adults With Obesity or Overweight and T2DM

Study testing weekly MET097 for adults with obesity and type 2 diabetes.

Recruiting
18-75 years
All
Phase 2

This study tests how well a new drug, MET097, helps people with obesity or being overweight and type 2 diabetes (T2DM) lose weight. The drug is a GLP-1 receptor agonist, which means it helps control insulin levels in the body. Participants will receive either MET097 or a placebo (a fake treatment) once a week through a shot under the skin for 28 weeks. After this, they will be checked for 4 weeks. Only adults aged 18-75 with a body mass index (BMI) between 27 and 50 can join. They must have had T2DM for at least 3 months and a stable weight before starting. People with certain health problems, like heart disease or specific types of cancer, cannot join.

  • This study lasts 28 weeks, with an additional 4-week follow-up.
  • Participants receive weekly treatments and need regular check-ups.
  • Participants are randomly assigned to MET097 or placebo groups.

If you qualify and join, this study might help you learn about weight loss options and how MET097 affects your T2DM and weight.

Study details
    Obesity in Diabetes
    Type 2 Diabetes Mellitus (T2DM)

NCT06897202

Metsera

12 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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