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A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1195, in 18- to 55-Year-Old Healthy Participants

Testing a new EBV vaccine for ages 18-55.

Recruiting
18-55 years
All
Phase 1

Study Overview: This study is testing a new vaccine, called mRNA-1195, to see if it's safe and causes any reactions. It targets the Epstein-Barr Virus (EBV), which can make people sick. The study involves two parts, starting with adults aged 18 to 55, and then focusing on younger adults aged 18 to 30. Participants must be healthy and, for safety, women who can have children need a negative pregnancy test and must use birth control during the study.

Key Points:

  • The study involves multiple visits and check-ups to ensure participant safety.
  • Participants must not have recent illnesses or certain medical conditions.
  • Participants cannot have had certain vaccines or donated a lot of blood recently.

Eligibility: To join, participants need to be generally healthy and either have had EBV before or not (depending on the study part). They must not be sick with a fever or have unstable health conditions. They should not have a history of heart-related inflammation or be on certain medications that affect the immune system.

Study details
    Epstein-Barr Virus Infection

NCT05831111

ModernaTX, Inc.

11 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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