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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

Testing Tezepelumab for adults with moderate to severe COPD symptoms.

Recruiting
40-80 years
All
Phase 3

This study tests a medicine called tezepelumab to see if it helps adults with moderate to very severe COPD (Chronic Obstructive Pulmonary Disease). COPD is a lung disease that makes it hard to breathe. The study is "randomized," meaning participants are chosen by chance, and "double-blind," meaning neither the doctors nor the participants know who gets the real medicine or a "placebo," a fake treatment. The study lasts up to 76 weeks with monthly injections and a 12-week follow-up without treatment. To join, you should be 40-80 years old, have had COPD for at least a year, and have had some serious flare-ups in the past year. Smokers or former smokers with a certain smoking history can join.

  • Participation requires monthly visits for up to 76 weeks.
  • Eligibility includes specific age, smoking history, and COPD severity.
  • Participants must not have asthma or other lung diseases.
Study details
    Chronic Obstructive Pulmonary Disease (COPD)

NCT06878261

AstraZeneca

28 June 2025

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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