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A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

Exploring tirzepatide for psoriatic arthritis in overweight patients.

Recruiting
18 years and older
All
Phase 4

This study will explore how adding **tirzepatide** (a new medicine) to **ixekizumab** (a medicine already being used) works for people with **Psoriatic Arthritis (PsA)**, which is a disease that causes joint pain and skin problems, and who are **overweight** or have **obesity**. People in the study have to have a **Body Mass Index (BMI)** of 27 kg/m² or more. The **BMI** is a number that shows if a person is at a healthy weight for their height. The study will last for up to **12 months**.

  • The study will require participants to have been using ixekizumab for about 3 months.
  • Participants must not have used tirzepatide or similar medicines before.
  • Participants need to be available for up to a year to complete the study.

People cannot join if they have certain health issues like severe eye problems, some types of cancer, or other serious conditions. If you're considering joining, talk to your doctor to see if it's right for you.

Study details
    Psoriatic Arthritis
    Overweight or Obesity

NCT06864026

Eli Lilly and Company

7 March 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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