This study is about using a hormone called progesterone in transgender women who are already on gender-affirming hormone therapy (GAHT), which includes medicines like estrogen. The goal is to see if progesterone helps with things like feeling better mentally, sleep, breast growth, and heart health. Some studies show progesterone might have risks like blood clots or liver issues, but more research is needed. This study uses a type of progesterone called micronized progesterone to see if it is safer and effective.

• The study is for transgender women on GAHT for at least 6 months.
• Participants cannot have certain health issues, like heart or liver disease.
• The study aims to find out if progesterone helps with life quality and if there are any risks.

This study is important to help doctors make better decisions about using progesterone in hormone therapy. If interested, make sure you meet the health criteria and understand the possible risks and benefits before joining.