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A Study to Assess the Efficacy and Safety of Induction Therapy With RO7790121 in Participants With Moderately to Severely Active Ulcerative Colitis

Testing a new treatment for moderate to severe ulcerative colitis.

Recruiting
16-80 years
All
Phase 3

This study is looking at how well a new treatment called RO7790121 works for people with *ulcerative colitis (UC)*, a condition causing inflammation in the colon, and how safe it is. The study is **Phase III**, which means it's in the final testing stage before possibly becoming available to the public. It is *double-blind* and *placebo-controlled*, meaning neither you nor the researchers will know if you're getting the real treatment or a placebo (a fake treatment) until the study ends.

To join, you must be diagnosed with moderate to severe UC, weigh at least 40 kilograms, and have tried other UC treatments without success. You can't join if you have specific complications or other conditions, like Crohn's disease or active infections.

  • **Study Length**: Not specified, but usually lasts several months.
  • **Visits Required**: You will need to visit the study center for check-ups and treatment.
  • **Risks**: Potential side effects like those from other UC treatments, and risks related to not knowing if you are receiving the real treatment.
Study details
    Moderately to Severely Active Ulcerative Colitis

NCT06588855

Hoffmann-La Roche

14 June 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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