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A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

Exploring LY4006895 for early Alzheimer's symptoms in healthy participants.

Recruiting
45-85 years
All
Phase 1

The study is testing the safety of a drug called LY4006895 on people with early Alzheimer's Disease (AD) and healthy volunteers. Alzheimer's Disease is a condition that affects memory and thinking. The study has two parts. Part A will last about 29 weeks and involves giving one dose of the drug to healthy people. Part B will last about 61 weeks and involves giving multiple doses to those with early AD symptoms. The study checks how the drug moves in the blood and how long it stays in the body.

  • Healthy people and those with early AD can join, but they must not have other serious illnesses.
  • Participants for Part B must have up to 2 study partners who can help with the study visits and stay in contact.
  • Women who are pregnant or breastfeeding cannot join, and participants must not have used certain drugs recently.

Participants will need to do blood tests and attend visits. It is important for each person to feel comfortable with the time and commitment needed for the study.

Study details
    Alzheimer Disease
    Healthy

NCT06657768

Eli Lilly and Company

7 March 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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