This study is a **safety check** for a medicine called **SMOFlipid**. It looks at its effects on patients needing food through a tube for at least 8 weeks. This is called **parenteral nutrition (PN)**, which means getting nutrients directly into the blood. The study wants to see if patients might develop problems like **EFAD** (essential fatty acid deficiency) or **PNAC** (parenteral nutrition-associated cholestasis), which are conditions related to nutrition and liver function. **Who can join?** Patients older than 1 month who need PN, getting most of their food this way, can join. They must have written consent from themselves or a guardian. **Who cannot join?** People who have allergies to fish, egg, soybean, or peanuts, or have certain health issues like liver or heart problems, or are pregnant, cannot participate. **Key Points:** - **Study Length:** 8 weeks or longer with regular check-ups. - **Visits:** Frequent visits to assess health and nutrition. - **Risks:** Possible side effects include liver issues and nutrient deficiencies. **Important:** Always discuss with your doctor if this study is right for you.